Organ Donation and
Transplantation Provides Second Life to Thousands of People
Organ
donation and transplantation provides a second chance at life for thousands of
people each year. The growing disparity between the rich and poor, demand for
human organs and availability of technology in the country makes the trading of
organs a quick means to riches for some and a relief for others. Invariably
Organ trade leads to exploitation of the poverty-stricken people by tempting
them with financial gains to meet their immediate short-term financial needs.
Making
organs a commodity is fraught with erosion of social, moral, and ethical values
and is not an alternative that can be acceptable to meet organ requirements in
a civilized society. The World
Health Organization (WHO) in its statement on the sale of organs clearly states
that it violates the Universal Declaration of Human Rights as well as its own
constitution: “The human body and its parts cannot be the subject of commercial
transactions. Accordingly, giving or receiving payment… for organs should be
prohibited.”
Each
year hundreds of Indians die while waiting for an organ transplant. The reason:
there is acute imbalance between the number of organs donated and the number of
people waiting for a transplant. While 2.1 lakh Indians
require kidney transplantation annually, but only 3000 – 4000 kidney
transplants are done. The situation is not very different in relation to heart
transplants. While annually around 4,000–5,000 patients in India require a
heart transplant, so far only 100 heart transplants have been conducted across
the country. According to the National Programme for Control of Blindness
(NPCB) 2012-13 report, only 4,417 corneas were available in 2012-13 against a
whopping requirement of 80,000-1, 00,000 per year. There are currently
over 120 transplant centres in
India
performing approximately 3,500 to 4,000 kidney transplants annually. Out of
these four centres undertake approximately 150 to 200 liver transplants
annually while some do an occasional heart transplant.
Finding a donor is the main issue in the
country. Lack of awareness and improper infrastructure facilities are the main
reasons behind the existing scenario. Administrative hurdles and conservative
mindset further affect organ transplantation scenario in India . There are a lot
of myths associated with organ donation which needs to be addressed to solve
this problem. Most Indians generally believe that it is against the nature and
religion that body parts are mutilated. Some are suspicious that the hospital
staff may not work hard to save their lives if they want organs. Others believe
that there might be a temptation to declare them dead before they are actually
dead. Lack of a
centralised registry for organ donation, acts as another major hurdle for the
people to donate organs or get data about donors. Also, there is a
problem of certifying brain deaths; if people are not aware of brain deaths, it becomes difficult to convince the
relatives of the patients for organ donation.
Kidney
transplants in India first
started in the 1970s and since then India has been a leading country in
this field on the Asian sub-continent. The evolutionary history of transplants
in the last four decades has witnessed commerce in organ donation becoming an integral
part of the program. The Government passed the Transplantation of Human Organ
Act (THO) in 1994 which made unrelated transplants illegal and deceased
donation a legal option with the acceptance of brain death. Overcoming organ
shortage by tapping into the pool of brain-dead patients was expected to curb
the unrelated transplant activity. But, despite the THO Act, neither has the
commerce stopped nor have the number of deceased donors increased to take care
of organ shortage. The concept of brain death has never been promoted or widely
publicized. Most unrelated transplants currently are being done with the
approval from an Authorization committee.
Government
of India
enacted the ‘Transplantation of Human Organs (Amendment) Act in 2011 which made
provisions for simplifying the procedure for human organ donation. The
provisions included retrieval centres and their registration for retrieval of
organs from deceased donors, swap donation and a mandatory inquiry by the
registered medical practitioner of a hospital in consultation with transplant
coordinator (if available) from the near relative(s) of potential donor
admitted in Intensive Care Unit and informing them about the option to donate
and if they consent to donate, inform the retrieval centre for retrieval of
organs.
In India , the
potential for deceased donation is huge due to the high number of fatal road
traffic accidents and this pool is yet to be tapped. At any given time, every
major city would have 8 – 10 brain deaths in various ICUs. Some 4 – 6% of all
hospital deaths are due to brain death. In India , road accidents account for
around 1.4 lakh deaths annually. Out of these, almost
65% sustain severe head injuries as per an AIIMS, Delhi , study. This means there are almost 90,000 patients who may
be brain dead.
It is not that people don’t want to donate, but that
there are no mechanisms in hospitals to identify and certify brain deaths.
Plus, no one empowers the relatives of a brain-dead person to save lives by
donating his organs. Anyone from a child to an elderly person can be a donor.
Organ donation from the brain dead – also referred to a cadaveric donation is
still very low in India .
While Spain has 35 organ donors per million people, Britain has 27 donors, US
26 and Australia 11, India’s count stands at a mere 0.16 per million people.
Signing a donor card is the first step in making your
wishes about donation known. A donor card is not a legal document but an
expression of one’s willingness to donate. While signing a donor card
demonstrates one’s desire to donate organ after death, letting the family or
friends know about the decision is very important. That is because family
members will be asked to give consent for the donation. The decision will be
considered final when they give consent. Vital organs such as heart, liver,
lungs, kidneys, pancreas and intestines, and tissues such as corneas, heart
valves, skin, bones, ligaments, tendons, veins, etc. can be donated in case of
brain death.
The proposed Transplantation of Human Organs and Tissues
Rules, 2013 has many provisions to remove the impediments to organ donation
while curbing misuse/misinterpretation of the rules. To mention a few;
· When the donor is unrelated and if
donor and/or recipient belong to a State/ Union Territory ,
other than the State/Union Territory where the transplantation is proposed to
be undertaken, “No Objection Certificate” from the State/Union Territory of
domicile of donor and/ or recipient is required. “No Objection Certificate”
will not be required for near relatives and Swap donation cases.
· The quorum of the Authorisation
Committee should be minimum four and is not complete without the participation
of the Chairman, Secretary (Health) or nominee and Director of Health Services
or nominee.
· Every authorised transplantation
centre must have its own website. The Authorisation Committee is required to
take final decision within twenty four hours of holding the meeting for grant
of permission or rejection for transplant and the decision of the Authorisation
Committee should be displayed on the notice board of the hospital and the
website within twenty four hours of taking the decision. The website of
transplantation centre shall be linked to State/Regional/National Networks
through online system for organ procurement, sharing and transplantation.
· There would be an apex national
networking organization at the centre. There would also be regional and State
level networking organizations where large of number of transplantation of organ(s)
or tissue (s) are performed. The State units would be linked to hospitals,
Organ/Tissue matching Labs and Tissue Banks within their area and also to
regional and national networking organisations. Such networks shall coordinate
procurement, storage, transportation, matching, allocation and transplantation
of organs/tissues and shall develop norms and standard operating procedures.
· A National Registry on Donors and
recipients of Human Organ and Tissue accessible on-line through dedicated website
having National, Regional and State level specificities will come into force.
National/Regional registry shall be compiled based on similar registries at
State level. The identity of the people in the database shall not be in public
domain.
Accordingly, the Government is going to set up
an online network under the National Organ and Tissue Transplant
Organisation (NOTTO). The online service will be able to connect people
directly to the donor. OTTO, an autonomous body under the Health ministry, would
be the nodal agency coordinating all organ transplants in the country. All
hospitals in the country, whether private, public or district-level health
centres, will be part of the network. Apart from NOTTO, four regional centres
would also be set up across the country.
To conclude, the emerging field of regenerative
medicine may allow scientists and engineers to create organs to be
re-grown from the patient's own cells (stem cells, or cells extracted from the
failing organs).This would not only improve the availability of compatible
organs but also would address the socio-ethical issues attached with it.
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